Manipulation types

Various manipulation types are available to modulate neural activity, study brain function, and potentially treat neurological and psychiatric disorders.

Deep brain stimulation (DBS)
Electromagnetic field stimulation
Electrical stimulation
Liquid perturbation
Micro perfusion
Optogenetic stimulation
Pharmacological inhalation
Pharmacological injection
Pharmacological superfusion
Sound stimulation
Thermal perturbation
Transcranial Electrical Stimulation
Transcranial Magnetic Stimulation (TMS)
Ultrasound stimulation
Manipulation API access

Deep brain stimulation (DBS)

Field	Description
`Amplitude (A)`	Amplitude of the stimulation in Amperes
`Duration (s)`	Duration of the stimulation in seconds
`Stimulation profile`	Profile of the stimulation (e.g., Amplitude Modulated)
`Duty cycle`	Duty cycle of the stimulation
`Repetitions`	Number of repetitions of the stimulation
`Injection polarity`	Polarity of the stimulation injection
`Closed loop`	Whether the stimulation is closed-loop or not

Electromagnetic field stimulation

Field	Description
`Amplitude (V)`	Amplitude of the stimulation in Volts
`Duration`	Duration of the stimulation
`Stimulation profile`	Profile of the stimulation (e.g., Amplitude Modulated)
`Duty cycle`	Duty cycle of the stimulation
`Repetitions`	Number of repetitions of the stimulation
`Injection polarity`	Polarity of the stimulation injection
`Closed loop`	Whether the stimulation is closed-loop or not

Electrical stimulation

Field	Description
`Amplitude (V)`	Amplitude of the stimulation in Volts
`Duration (s)`	Duration of the stimulation in seconds
`Stimulation profile`	Profile of the stimulation (e.g., Amplitude Modulated)
`Duty cycle`	Duty cycle of the stimulation
`Repetitions`	Number of repetitions of the stimulation
`Injection polarity`	Polarity of the stimulation injection
`Closed loop`	Whether the stimulation is closed-loop or not

Liquid perturbation

Field	Description
`Liquid agent`	Name or type of the liquid agent used
`Concentration (mg/mL)`	Concentration of the liquid agent in mg/mL
`Volume (µL)`	Volume of the liquid agent in microliters
`Perturbation profile`	Profile of the perturbation (e.g., Bolus Injection)
`Repetitions`	Number of repetitions of the perturbation
`Flow rate (µL/min)`	Flow rate of the liquid agent in µL/min
`Closed loop`	Whether the perturbation is closed-loop or not

Micro perfusion

Field	Description
`Liquid agent`	Name or type of the liquid agent used
`Concentration (mg/mL)`	Concentration of the liquid agent in mg/mL
`Volume (µL)`	Volume of the liquid agent in microliters
`Perturbation profile`	Profile of the perturbation (e.g., Bolus Injection)
`Repetitions`	Number of repetitions of the perfusion
`Flow rate (µL/min)`	Flow rate of the liquid agent in µL/min
`Closed loop`	Whether the perfusion is closed-loop or not

Optogenetic stimulation

Field	Description
`Power (mW)`	Power of the light stimulation in milliwatts
`Amplitude (A)`	Amplitude of the stimulation in Amperes
`Stimulation profile`	Profile of the stimulation (e.g., Amplitude Modulated)
`Duration (s)`	Duration of the stimulation in seconds
`Duty cycle`	Duty cycle of the stimulation
`Repetitions`	Number of repetitions of the stimulation
`Wavelength (nm)`	Wavelength of the light in nanometers
`Closed loop`	Whether the stimulation is closed-loop or not

Pharmacological inhalation

Field	Description
`Liquid agent`	Name or type of the liquid agent used
`Concentration (mg/mL)`	Concentration of the liquid agent in mg/mL
`Flow rate (µL/min)`	Flow rate of the liquid agent in µL/min
`Stimulation profile`	Profile of the stimulation (e.g., Bolus Inhalation)
`Volume (µL)`	Volume of the liquid agent in microliters
`Repetitions`	Number of repetitions of the inhalation
`Analgesic`	Whether the agent is an analgesic
`Sedative`	Whether the agent is a sedative
`Closed loop`	Whether the inhalation is closed-loop or not

Pharmacological injection

Field	Description
`Liquid agent`	Name or type of the liquid agent used
`Concentration (mg/mL)`	Concentration of the liquid agent in mg/mL
`Volume (µL)`	Volume of the liquid agent in microliters
`Injection profile`	Profile of the injection (e.g., Bolus Injection)
`Repetitions`	Number of repetitions of the injection
`Flow rate (µL/min)`	Flow rate of the liquid agent in µL/min
`Closed loop`	Whether the injection is closed-loop or not

Pharmacological superfusion

Field	Description
`Liquid agent`	Name or type of the liquid agent used
`Concentration (mg/mL)`	Concentration of the liquid agent in mg/mL
`Volume (µL)`	Volume of the liquid agent in microliters
`Superfusion profile`	Profile of the superfusion (e.g., Bolus Injection)
`Repetitions`	Number of repetitions of the superfusion
`Flow rate (µL/min)`	Flow rate of the liquid agent in µL/min
`Closed loop`	Whether the superfusion is closed-loop or not

Sound stimulation

Field	Description
`Amplitude (dB)`	Amplitude of the sound stimulation in decibels
`Duration (s)`	Duration of the stimulation in seconds
`Stimulation profile`	Profile of the stimulation (e.g., Amplitude Modulated)
`Duty cycle`	Duty cycle of the stimulation
`Repetitions`	Number of repetitions of the stimulation
`Closed loop`	Whether the stimulation is closed-loop or not

Thermal perturbation

Field	Description
`Amplitude (°C)`	Amplitude of the temperature change in degrees Celsius
`Duration (s)`	Duration of the perturbation in seconds
`Thermal profile`	Profile of the thermal perturbation (e.g., Amplitude Modulated)
`Duty cycle`	Duty cycle of the perturbation
`Repetitions`	Number of repetitions of the perturbation
`Closed loop`	Whether the perturbation is closed-loop or not

Transcranial Electrical Stimulation

Field	Description
`Amplitude (mA)`	Amplitude of the stimulation in milliamperes
`Duration (s)`	Duration of the stimulation in seconds
`Stimulation profile`	Profile of the stimulation (e.g., Amplitude Modulated)
`Duty cycle`	Duty cycle of the stimulation
`Repetitions`	Number of repetitions of the stimulation
`Injection polarity`	Polarity of the stimulation injection
`Closed loop`	Whether the stimulation is closed-loop or not

Transcranial Magnetic Stimulation (TMS)

Field	Description
`Amplitude (mA)`	Amplitude of the stimulation in milliamperes
`Duration (s)`	Duration of the stimulation in seconds
`Stimulation profile`	Profile of the stimulation (e.g., Amplitude Modulated)
`Duty cycle`	Duty cycle of the stimulation
`Repetitions`	Number of repetitions of the stimulation
`Injection polarity`	Polarity of the stimulation injection
`Closed loop`	Whether the stimulation is closed-loop or not

Ultrasound stimulation

Field	Description
`Amplitude (V)`	Amplitude of the stimulation in Volts
`Duration (s)`	Duration of the stimulation in seconds
`Duty cycle`	Duty cycle of the stimulation
`Stimulation profile`	Profile of the stimulation (e.g., Amplitude Modulated)
`Repetitions`	Number of repetitions of the stimulation
`Injection polarity`	Polarity of the stimulation injection
`Closed loop`	Whether the stimulation is closed-loop or not

Manipulation API access

The API allows for programmable access to Manipulations, enabling you to read, edit, and delete manipulations through the API. Learn more about the manipulations’ fields and data structure on the Manipulation API page.